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Nek7M1Btlr
Chemically induced Allele Detail
Nomenclature
Symbol: Nek7M1Btlr
Name: NIMA (never in mitosis gene a)-related expressed kinase 7; mutation 1, Bruce Beutler
MGI ID: MGI:5690178
Synonyms: Cuties, Nek7Cu
Gene: Nek7  Location: Chr1:138483837-138619757 bp, - strand  Genetic Position: Chr1, 60.82 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU mutagenesis induced a T to A transversion at base pair 138,544,242 (v38) on chromosome 1, or base pair 75,538 in the GenBank genomic region NC_000067, corresponding to residue 332 in exon 3 of 10 total exons. The mutation results in a substitution of cysteine (C) to a premature stop codon at residue 53. (J:225042)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nek7 Mutation:  11 strains or lines available
References
Original:  J:225042 Shi H, et al., Mutagenetix entry for Cuties. MGI Direct Data Submission. 2015;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/04/2019
MGI 6.14
The Jackson Laboratory