Summary |
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Variant origin |
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Variant description |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:197549Linkage analysis was performed on 266 female (B6.129P2-Apoetm1Unc/J x C.129P2(B6)-Apoetm1Unc)F2 intercross mice using 130 SNP markers to identify QTL associated with susceptibility to athleroscotic carotid lesion. QTL mapping was performed using a nonparametric method. QTL Cath3 maps to 18.99 - 59.69 cM on Chromosome 13 with a peak LOD score of 4.292 at 48.99 cM in linkage with athleroscotic carotid lesion incidence. B6.129P2-Apoetm1Unc/J alleles confer increased susceptibility to athleroscotic carotid lesion with an additive mode of inheritance. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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