Ngfr^tm1Ejco
Targeted Allele Detail

Summary

• Symbol: Ngfr^tm1Ejco
• Name: nerve growth factor receptor (TNFR superfamily, member 16); targeted mutation 1, Elizabeth J Coulson
• MGI ID: MGI:5688654
• Synonyms: p75^fl
• Gene: Ngfr Location: Chr11:95459644-95478524 bp, - strand Genetic Position: Chr11, 59.01 cM
• Alliance: Ngfr^tm1Ejco page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216610
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A loxP site was inserted in the 5' UTR and a polyA-mCherry cassette in inverse orientation and loxP site were inserted in intron 1 via homologous recombination. The loxP sites were mutated so that recombination leads to inversion rather than excision of the sequence. (J:216610)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ngfr Mutation: 32 strains or lines available

References

• Original: J:216610 Boskovic Z, et al., The role of p75NTR in cholinergic basal forebrain structure and function. J Neurosci. 2014 Sep 24;34(39):13033-8
• All: 4 reference(s)