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Jak1tm1.1Kuw
Targeted Allele Detail
Nomenclature
Symbol: Jak1tm1.1Kuw
Name: Janus kinase 1; targeted mutation 1.1, Kay-Uwe Wagner
MGI ID: MGI:5688350
Gene: Jak1  Location: Chr4:101152367-101265282 bp, - strand  Genetic Position: Chr4, 46.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:235355
Parent Cell Line:  RW-4 (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThis allele is a derivative of Jak1tm1Kuw in which the loxP-flanked exon 2 was deleted in the germline by Cre-mediated recombination, leaving the frt-flanked PGK-neo in the intron following the floxed region. (J:235355)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Jak1 Mutation:  11 strains or lines available
References
Original:  J:235355 Sakamoto K, et al., Generation of Janus kinase 1 (JAK1) conditional knockout mice. Genesis. 2016 Nov;54(11):582-588
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory