Pou4f1^tm2.1Et
Targeted Allele Detail

Summary

• Symbol: Pou4f1^tm2.1Et
• Name: POU domain, class 4, transcription factor 1; targeted mutation 2.1, Eric Turner
• MGI ID: MGI:5662420
• Synonyms: Pou4f1^flox
• Gene: Pou4f1 Location: Chr14:104699112-104705435 bp, - strand Genetic Position: Chr14, 54.21 cM, cytoband E1-E3
• Alliance: Pou4f1^tm2.1Et page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:216164
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked TK-neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:216164)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou4f1 Mutation: 16 strains or lines available

References

• Original: J:216164 Hsu YW, et al., Role of the dorsal medial habenula in the regulation of voluntary activity, motor function, hedonic state, and primary reinforcement. J Neurosci. 2014 Aug 20;34(34):11366-84
• All: 3 reference(s)