Rhoa^tm1.1Kft
Targeted Allele Detail

Summary

• Symbol: Rhoa^tm1.1Kft
• Name: ras homolog family member A; targeted mutation 1.1, Kimberley F Tolias
• MGI ID: MGI:5660878
• Synonyms: RhoA^fl
• Gene: Rhoa Location: Chr9:108183359-108215142 bp, + strand Genetic Position: Chr9, 59.2 cM
• Alliance: Rhoa^tm1.1Kft page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:203741
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 3 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:203741)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rhoa Mutation: 75 strains or lines available

References

• Original: J:203741 Mulherkar S, et al., The small GTPase RhoA is required for proper locomotor circuit assembly. PLoS One. 2013;8(6):e67015
• All: 3 reference(s)