Cfap126^tm2.1Heli
Targeted Allele Detail

Summary

• Symbol: Cfap126^tm2.1Heli
• Name: cilia and flagella associated protein 126; targeted mutation 2.1, Heiko Lickert
• MGI ID: MGI:5660821
• Synonyms: Fltp^ZV
• Gene: Cfap126 Location: Chr1:170941487-170954536 bp, + strand Genetic Position: Chr1, 78.96 cM
• Alliance: Cfap126^tm2.1Heli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215971
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A genomic region spanning the entire open reading frame (exons 2-6) was replaced with a construct including an NLS-lacZ, viral T2A sequence, histone 2B, Venus reporter gene, and SV40-pA and a floxed neo cassette via homologous recombination. Cre mediated recombination removed the neo cassette. (J:215971)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cfap126 Mutation: 15 strains or lines available

References

• Original: J:215971 Gegg M, et al., Flattop regulates basal body docking and positioning in mono- and multiciliated cells. Elife. 2014;3
• All: 4 reference(s)