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Targeted Allele Detail
Symbol: Ccr7tm1.1Dnc
Name: chemokine (C-C motif) receptor 7; targeted mutation 1.1, Donald Cook
MGI ID: MGI:5660365
Synonyms: Ccr7gfp
Gene: Ccr7  Location: Chr11:99144199-99155077 bp, - strand  Genetic Position: Chr11, 62.92 cM, cytoband D
Germline Transmission:  Earliest citation of germline transmission: J:223508
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6NTac
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsThe targeting vector contains a loxP-flanked neomycin cassette and sequence encoding Enhanced Green Fluorescent Protein was used to disrupt the coding region of the Ccr7 gene. Transient transfection with a cre-expressing plasmid DNA removed the selection cassette. (J:223508)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ccr7 Mutation:  15 strains or lines available
Original:  J:223508 Nakano H, et al., Migratory properties of pulmonary dendritic cells are determined by their developmental lineage. Mucosal Immunol. 2013 Jul;6(4):678-91
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.15
The Jackson Laboratory