Pacsin1^tm1.1Bqu
Targeted Allele Detail

Summary

• Symbol: Pacsin1^tm1.1Bqu
• Name: protein kinase C and casein kinase substrate in neurons 1; targeted mutation 1.1, Britta Qualmann
• MGI ID: MGI:5660311
• Synonyms: syndapin I KO
• Gene: Pacsin1 Location: Chr17:27874565-27930092 bp, + strand Genetic Position: Chr17, 14.59 cM, cytoband B1
• Alliance: Pacsin1^tm1.1Bqu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:180017
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1 and a loxP site and an FRT flanked neo cassette were inserted downstream of exon 1 via homologous recombination. Cre mediated recombination removed exon 1. (J:180017)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pacsin1 Mutation: 27 strains or lines available

References

• Original: J:180017 Koch D, et al., Proper synaptic vesicle formation and neuronal network activity critically rely on syndapin I. EMBO J. 2011 Dec 14;30(24):4955-69
• All: 2 reference(s)