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Targeted Allele Detail
Symbol: Septin7tm1.1Mgl
Name: septin 7; targeted mutation 2.1, Matthia Gaestel
MGI ID: MGI:5660261
Synonyms: Sept7del
Gene: Septin7  Location: Chr9:25252439-25308571 bp, + strand  Genetic Position: Chr9, 10.25 cM
Germline Transmission:  Earliest citation of germline transmission: J:223786
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 4. A second loxP site was inserted downstream of exon 4. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 4. (J:223786)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Septin7 Mutation:  25 strains or lines available
Original:  J:223786 Menon MB, et al., Genetic deletion of SEPT7 reveals a cell type-specific role of septins in microtubule destabilization for the completion of cytokinesis. PLoS Genet. 2014 Aug;10(8):e1004558
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory