Slc6a4^em1Ionsz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc6a4^em1Ionsz
• Name: solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; endonuclease-mediated mutation 1, Qiang Sun
• MGI ID: MGI:5660257
• Gene: Slc6a4 Location: Chr11:76889429-76923166 bp, + strand Genetic Position: Chr11, 46.18 cM
• Alliance: Slc6a4^em1Ionsz page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/1)F1

Mutation description

• Allele Type: Endonuclease-mediated (Reporter)
• Mutation: Insertion
• Mutation details: The CRISPR/Cas9 system was used to inserted behind the last exon a viral 2A oligopeptide that mediates ribosomal skipping and the light-activated ion channel channelrhodopsin-2 (ChR2) fused to an enhanced yellow fluorescent protein. (J:223507)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a4 Mutation: 58 strains or lines available

References

• Original: J:223507 Li Y, et al., Direct data submission for endonuclease mediated alleles from the Institute of Neuroscience, Chinese Academy of Sciences. MGI Direct Data Submission. 2015
• All: 1 reference(s)