Gt(ROSA)26Sor^{tm1(CAG-GCaMP5)Ryba}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-GCaMP5)Ryba}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nicholas JP Ryba
• MGI ID: MGI:5649028
• Synonyms: Rosa26^GCaMP5, Rosa^GCaMP5
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-GCaMP5)Ryba} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223139
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting construct introduced a CAG promoter driving ubiquitous expression of the calcium indicator GCaMP5 reporter. A floxed stop cassette prevents reporter expression. (J:223139, J:223216)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:223139 Ye J, et al., hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3020-9
• All: 3 reference(s)