Hprt1^{tm7.1(CAG-Atp6ap2)Geno}
Targeted Allele Detail

Summary

• Symbol: Hprt1^{tm7.1(CAG-Atp6ap2)Geno}
• Name: hypoxanthine phosphoribosyltransferase 1; targeted mutation 7.1, Genoway
• MGI ID: MGI:5646017
• Synonyms: Atp6ap2/PRR^lox
• Gene: Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
• Alliance: Hprt1^{tm7.1(CAG-Atp6ap2)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213945
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Hprt1^{tm7.1(CAG-Atp6ap2)Geno} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Atp6ap2 (MGI:1917745)

• Mutation details: A construct containing a CAG promoter, floxed stop cassette, and mouse Atp6ap2 cDNA was inserted. Cre mediated recombination removed the neo cassette. (J:213945)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hprt1 Mutation: 1280 strains or lines available

References

• Original: J:213945 Rosendahl A, et al., Increased expression of (pro)renin receptor does not cause hypertension or cardiac and renal fibrosis in mice. Lab Invest. 2014 Aug;94(8):863-72
• All: 2 reference(s)