Tg(Tyr)2231Lmon
Transgene Detail

Summary

• Symbol: Tg(Tyr)2231Lmon
• Name: transgene insertion 2231, Lluis Montoliu
• MGI ID: MGI:5645920
• Synonyms: TYR5
• Transgene: Tg(Tyr)2231Lmon Location: unknown
• Alliance: Tg(Tyr)2231Lmon page

Transgene origin

• Strain of Origin: Hsd:NMRI

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Transgenic mouse line carrying 8 copies of a reporter tyrosinase construct (TYR5), described previously allowing pigmentation rescue of albino recipient strains and whose expression level is fully dependent on the site of integration and the number of copies of the mouse line. This line expresses intermediate TYR5 levels, resulting in pigmented eyes and grey uniform coat color pigmentation. (J:185183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:185183 Furlan-Magaril M, et al., An insulator embedded in the chicken alpha-globin locus regulates chromatin domain configuration and differential gene expression. Nucleic Acids Res. 2011 Jan;39(1):89-103
• All: 1 reference(s)