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Tg(ANPEP)861Mmul
Transgene Detail
Summary
Symbol: Tg(ANPEP)861Mmul
Name: transgene insertion 861, Mathias Muller
MGI ID: MGI:5645779
Synonyms: Tg(APN)861
Transgene: Tg(ANPEP)861Mmul  Location: unknown  
Alliance: Tg(ANPEP)861Mmul page
Transgene
origin
Strain of Origin:  ICR
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ANPEP)861Mmul expresses 1 gene
 
Mutation detailsA human cDNA is expressed under the control of 11-kb of the human 5 gene regulatory sequences. Ten transgenic lines were created (270, 275, 313, 315, 735, 746, 795, 861, 884, and 902). Mouse lines 270 and 861 expressed the highest levels of hAPN mRNA and were studied further. (J:99728)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
References
Original:  J:99728 Lassnig C, et al., Development of a transgenic mouse model susceptible to human coronavirus 229E. Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8275-80
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/22/2022
MGI 6.22
The Jackson Laboratory