Tg(tetO-Ppp3ca*)5Igta
Transgene Detail

Summary

• Symbol: Tg(tetO-Ppp3ca*)5Igta
• Name: transgene insertion 5, Ignacio Torres-Aleman
• MGI ID: MGI:5645759
• Synonyms: deltaCnA5, TetOdeltaCnA, Tg(tetO-CnA)5Igta
• Transgene: Tg(tetO-Ppp3ca*)5Igta Location: unknown
• Alliance: Tg(tetO-Ppp3ca*)5Igta page

Transgene origin

• Strain of Origin: C57BL/6 x SJL

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Ppp3ca*)5Igta expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ppp3ca (MGI:107164)

• Mutation details: This construct expresses a mouse cDNA encoding a constitutively active form of the catalytic subunit of calcineurin (CnA) under the control of the tTA-sensitive TetO promoter. (J:145253)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:145253 Fernandez AM, et al., Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci. 2007 Aug 15;27(33):8745-56
• All: 1 reference(s)