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Tg(tetO-Ppp3ca*)5Igta
Transgene Detail
Nomenclature
Symbol: Tg(tetO-Ppp3ca*)5Igta
Name: transgene insertion 5, Ignacio Torres-Aleman
MGI ID: MGI:5645759
Synonyms: deltaCnA5, TetOdeltaCnA, Tg(tetO-CnA)5Igta
Transgene: Tg(tetO-Ppp3ca*)5Igta  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6 x SJL
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    tTA
Mutation:    Insertion
 
Tg(tetO-Ppp3ca*)5Igta expresses 1 gene
 
Mutation detailsThis construct expresses a mouse cDNA encoding a constitutively active form of the catalytic subunit of calcineurin (CnA) under the control of the tTA-sensitive TetO promoter. (J:145253)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:145253 Fernandez AM, et al., Calcineurin in reactive astrocytes plays a key role in the interplay between proinflammatory and anti-inflammatory signals. J Neurosci. 2007 Aug 15;27(33):8745-56
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/20/2020
MGI 6.16
The Jackson Laboratory