Tg(Ttr-NR0B2)1Ital
Transgene Detail

Summary

• Symbol: Tg(Ttr-NR0B2)1Ital
• Name: transgene insertion 1, Iannis Talianidis
• MGI ID: MGI:5645742
• Synonyms: SHP-Tg
• Transgene: Tg(Ttr-NR0B2)1Ital Location: unknown
• Alliance: Tg(Ttr-NR0B2)1Ital page

Transgene origin

• Strain of Origin: (CBA/Ca x C57BL/10)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Ttr-NR0B2)1Ital expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  NR0B2 (8431)

  Nr0b2

  (MGI:1346344)

• Mutation details: The transgenic construct expresses human NR0B2 (HA-Tag) flagged under the mouse Ttr promoter. Hepatic SHP expression in this transgenic line is 7-fold above endogenous levels. (J:134619)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:134619 Boulias K, et al., Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. EMBO J. 2005 Jul 20;24(14):2624-33
• All: 1 reference(s)