Tg(TNFRSF1B)1334Gkl
Transgene Detail

Summary

• Symbol: Tg(TNFRSF1B)1334Gkl
• Name: transgene insertion 1334, George Kollias
• MGI ID: MGI:5645560
• Synonyms: TgE1334
• Transgene: Tg(TNFRSF1B)1334Gkl Location: unknown
• Alliance: Tg(TNFRSF1B)1334Gkl page

Transgene origin

• Strain of Origin: CBA x C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(TNFRSF1B)1334Gkl expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNFRSF1B (7133)

  Tnfrsf1b

  (MGI:1314883)

• Mutation details: The entire human gene, including the 5' and 3' flanking regions was used to create transgenic mice. Expression patterns were comparable to the endogenous mouse gene, with the highest levels seen in lymphoid tissues, liver, and lung. Three transgenic lines were generated (TgE1322, TgE1334, and TgE1335) carrying various transgene copy numbers. (J:114744)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:114744 Douni E, et al., A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R. J Exp Med. 1998 Oct 5;188(7):1343-52
• All: 1 reference(s)