Lcn2^tm1.2Bara
Targeted Allele Detail

Summary

• Symbol: Lcn2^tm1.2Bara
• Name: lipocalin 2; targeted mutation 1.2, Jonathan Barasch
• MGI ID: MGI:5645261
• Gene: Lcn2 Location: Chr2:32274649-32277751 bp, - strand Genetic Position: Chr2, 22.09 cM, cytoband A3
• Alliance: Lcn2^tm1.2Bara page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213786
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 1 and an FRT and loxP flanked neo cassette was inserted in intron 5 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exons 2-5. (J:213786)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lcn2 Mutation: 30 strains or lines available

References

• Original: J:213786 Paragas N, et al., alpha-Intercalated cells defend the urinary system from bacterial infection. J Clin Invest. 2014 Jul 1;124(7):2963-76
• All: 2 reference(s)