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Tamm41tm1b(KOMP)Wtsi
Targeted Allele Detail
Summary
Symbol: Tamm41tm1b(KOMP)Wtsi
Name: TAM41 mitochondrial translocator assembly and maintenance homolog; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5644833
Synonyms: Tam41 null
Gene: Tamm41  Location: Chr6:114981342-115014837 bp, - strand  Genetic Position: Chr6, 53.14 cM, cytoband E3
Alliance: Tamm41tm1b(KOMP)Wtsi page
IMPC: Tamm41 gene page
Mutation
origin
Mutant Cell Line:  EPD0610_1_H07
Germline Transmission:  Earliest citation of germline transmission: J:94077
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: L1L2_Bact_P
 
Mutation detailsThe L1L2_Bact_P cassette was inserted at position 115025851 of Chromosome 6 upstream of exon 4. The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site. A third loxP site is inserted downstream of exon 4. Cre-mediated recombination removed the floxed neo cassette. Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:94077)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tamm41 Mutation:  18 strains or lines available
References
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory