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Gipc1tm1.1Mhsi
Targeted Allele Detail
Nomenclature
Symbol: Gipc1tm1.1Mhsi
Name: GIPC PDZ domain containing family, member 1; targeted mutation 1.1, Michael Simons
MGI ID: MGI:5644333
Synonyms: gipc1flox
Gene: Gipc1  Location: Chr8:84379306-84391323 bp, + strand  Genetic Position: Chr8, 40.22 cM, cytoband C3
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:221554
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the selection cassette and left exon 2 floxed. (J:221554)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gipc1 Mutation:  36 strains or lines available
References
Original:  J:221554 Moraes F, et al., Endothelial cell-dependent regulation of arteriogenesis. Circ Res. 2013 Oct 12;113(9):1076-86
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory