About   Help   FAQ
Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe
Transgene Detail
Nomenclature
Symbol: Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe
Name: transgene insertion, Andrzej Fertala
MGI ID: MGI:5643753
Synonyms: R992CProGFP
Transgene: Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Reporter)
Mutation:    Insertion
 
Tg(tetO/CMV-Col2a1*R992C,-GFP)#Afe expresses 1 gene
 
Mutation detailsThe collagen alpha1(II) chain containing a R992C amino acid substitution is under the control of the tetracycline response element-controlled cytomegalovirus (TRE-CMV) promoter. Two lines were created and this line carrying two copy numbers was analyzed. The pound symbol (#) is used because the line is not specified. (J:216945)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:216945 Arita M, et al., Mechanisms of Aberrant Organization of Growth Plates in Conditional Transgenic Mouse Model of Spondyloepiphyseal Dysplasia Associated with the R992C Substitution in Collagen II. Am J Pathol. 2015 Jan;185(1):214-29
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/05/2019
MGI 6.13
The Jackson Laboratory