Trp53^tm1Lejo
Targeted Allele Detail

Summary

• Symbol: Trp53^tm1Lejo
• Name: transformation related protein 53; targeted mutation 1, Leisa Johnson
• MGI ID: MGI:5641750
• Synonyms: Trp53^frt
• Gene: Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
• Alliance: Trp53^tm1Lejo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:187012
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• An FRT flanked allele was generated. No details provided. (J:187012)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp53 Mutation: 232 strains or lines available

References

• Original: J:187012 Singh M, et al., Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models. J Pathol. 2012 Aug;227(4):417-30
• All: 4 reference(s)