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Tg(ACTA1-DMD*)326Dua
Transgene Detail
Nomenclature
Symbol: Tg(ACTA1-DMD*)326Dua
Name: transgene insertion 326, Dongsheng Duan
MGI ID: MGI:5641706
Synonyms: deltaR4-23/deltaC
Transgene: Tg(ACTA1-DMD*)326Dua  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ACTA1-DMD*)326Dua expresses 1 gene
 
Mutation detailsThe transgenic construct contains a full length human dystrophin gene modified by the deletion of repeat 4 through repeat 23 and the C-terminus to generate a micro-dystrophin cDNA (deltaR4-23/deltaC) under the control of the human skeletal alpha 1 actin (ACTA1) promoter. (J:167308)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:167308 Li D, et al., Nitrosative stress elicited by nNOSmicro delocalization inhibits muscle force in dystrophin-null mice. J Pathol. 2011 Jan;223(1):88-98
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory