Gt(ROSA)26Sor^{tm2(Zfpm1)Pmt}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2(Zfpm1)Pmt}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Patrick Matthias
• MGI ID: MGI:5638935
• Synonyms: R26^FOG-1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2(Zfpm1)Pmt} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:215189
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm2(Zfpm1)Pmt} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Zfpm1 (MGI:1095400)

• Mutation details: RMCE using Gt(ROSA)26Sor^tm1Pmt replaced the hygromycin resistance cassette with a floxed neomycin resistance and stop cassette, the Zfpm1 sequence, an IRES and human CD2 reporter gene (hCD2t). (J:215189)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1095 strains or lines available

References

• Original: J:215189 Du Roure C, et al., Hematopoietic overexpression of FOG1 does not affect B-cells but reduces the number of circulating eosinophils. PLoS One. 2014;9(4):e92836
• All: 1 reference(s)