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Camk2btm1.1Ics
Targeted Allele Detail
Nomenclature
Symbol: Camk2btm1.1Ics
Name: calcium/calmodulin-dependent protein kinase II, beta; targeted mutation 1.1, Mouse Clinical Institute
MGI ID: MGI:5638541
Synonyms: CaMKIIbeta KO
Gene: Camk2b  Location: Chr11:5969644-6066362 bp, - strand  Genetic Position: Chr11, 3.89 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219040
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S2/SvPas
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsExons 7 and 8 were floxed by two LoxP sequences, followed by a frt-neo-frt cassette in intron 8. Floxed exons 7 and 8 and the neo cassette were then removed. Western analysis confirmed the absence of expression. (J:219040)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Camk2b Mutation:  77 strains or lines available
References
Original:  J:219040 Bachstetter AD, et al., Generation and behavior characterization of CaMKIIbeta knockout mice. PLoS One. 2014;9(8):e105191
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory