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Bmi1tm1.1Sjm
Targeted Allele Detail
Nomenclature
Symbol: Bmi1tm1.1Sjm
Name: Bmi1 polycomb ring finger oncogene; targeted mutation 1.1, Sean J Morrison
MGI ID: MGI:5638198
Synonyms: Bmi1fl
Gene: Bmi1  Location: Chr2:18677018-18686629 bp, + strand  Genetic Position: Chr2, 12.9 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213217
Parent Cell Line:  W4 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site and an FRT flanked neo cassette were inserted upstream the first coding exon and a loxP site was inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:213217)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Bmi1 Mutation:  18 strains or lines available
References
Original:  J:213217 Mich JK, et al., Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife. 2014;3:e02669
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory