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Tg(Scn10a-EGFP)ALmp
Transgene Detail
Nomenclature
Symbol: Tg(Scn10a-EGFP)ALmp
Name: transgene insertion A, The Laboratory of Molecular Physiology
MGI ID: MGI:5636777
Synonyms: Scn10a-EGFP
Transgene: Tg(Scn10a-EGFP)ALmp  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6N
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe transgene contains (from 5' to 3') the Na>V<1.8 putative promoter region (the 3.7 kbp sequence immediately upstream of a 24 kbp intron and transcriptional start site of the Scn10a gene) directing expression of an enhanced green fluorescent protein sequence (EGFP) followed by an SV40 early polyadenylation signal. Bright EGFP fluorescence is observed in peripheral sensory neurons, no EGFP expression is shown in sympathetic neurons. (J:220881)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:220881 Lu VB, et al., A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal. J Neurosci. 2015 May 20;35(20):8021-34
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory