Tg(Scn10a-EGFP)ALmp
Transgene Detail

Summary

• Symbol: Tg(Scn10a-EGFP)ALmp
• Name: transgene insertion A, The Laboratory of Molecular Physiology
• MGI ID: MGI:5636777
• Synonyms: Scn10a-EGFP
• Transgene: Tg(Scn10a-EGFP)ALmp Location: unknown
• Alliance: Tg(Scn10a-EGFP)ALmp page

Transgene origin

• Strain of Origin: C57BL/6N

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The transgene contains (from 5' to 3') the Na>V<1.8 putative promoter region (the 3.7 kbp sequence immediately upstream of a 24 kbp intron and transcriptional start site of the Scn10a gene) directing expression of an enhanced green fluorescent protein sequence (EGFP) followed by an SV40 early polyadenylation signal. Bright EGFP fluorescence is observed in peripheral sensory neurons, no EGFP expression is shown in sympathetic neurons. (J:220881)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:220881 Lu VB, et al., A 3.7 kb fragment of the mouse Scn10a gene promoter directs neural crest but not placodal lineage EGFP expression in a transgenic animal. J Neurosci. 2015 May 20;35(20):8021-34
• All: 1 reference(s)