Cilk1^tm1.1Tfur
Targeted Allele Detail

Summary

• Symbol: Cilk1^tm1.1Tfur
• Name: ciliogenesis associated kinase 1; targeted mutation 1.1, Takahisa Furukawa
• MGI ID: MGI:5636683
• Synonyms: ICK^-
• Gene: Cilk1 Location: Chr9:78016474-78079389 bp, + strand Genetic Position: Chr9, 43.56 cM, cytoband E1
• Alliance: Cilk1^tm1.1Tfur page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211665
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted into intron 2 and a second loxP site was inserted into intron 3 via homologous recombination. Cre mediated recombination removed exon 2. (J:211665)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cilk1 Mutation: 52 strains or lines available

References

• Original: J:211665 Chaya T, et al., ICK is essential for cell type-specific ciliogenesis and the regulation of ciliary transport. EMBO J. 2014 Jun 2;33(11):1227-42
• All: 2 reference(s)