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Targeted Allele Detail
Symbol: Ccl2tm1Dple
Name: chemokine (C-C motif) ligand 2; targeted mutation 1, David Pleasure
MGI ID: MGI:5636605
Synonyms: CCL2flx
Gene: Ccl2  Location: Chr11:82035577-82037452 bp, + strand  Genetic Position: Chr11, 49.82 cM, cytoband C-E1
Germline Transmission:  Earliest citation of germline transmission: J:211707
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exons 2-3 were floxed. (J:211707)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ccl2 Mutation:  9 strains or lines available
Original:  J:211707 Moreno M, et al., Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE. J Neurosci. 2014 Jun 11;34(24):8175-85
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory