Ccl2^tm1Dple
Targeted Allele Detail

Summary

• Symbol: Ccl2^tm1Dple
• Name: C-C motif chemokine ligand 2; targeted mutation 1, David Pleasure
• MGI ID: MGI:5636605
• Synonyms: CCL2^flx
• Gene: Ccl2 Location: Chr11:81926403-81928278 bp, + strand Genetic Position: Chr11, 49.82 cM, cytoband C-E1
• Alliance: Ccl2^tm1Dple page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211707
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exons 2-3 were floxed. (J:211707)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccl2 Mutation: 25 strains or lines available

References

• Original: J:211707 Moreno M, et al., Conditional ablation of astroglial CCL2 suppresses CNS accumulation of M1 macrophages and preserves axons in mice with MOG peptide EAE. J Neurosci. 2014 Jun 11;34(24):8175-85
• All: 1 reference(s)