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Ruvbl1tm1.1Hlee
Targeted Allele Detail
Summary
Symbol: Ruvbl1tm1.1Hlee
Name: RuvB-like AAA ATPase 1; targeted mutation 1.1, Ho Lee
MGI ID: MGI:5635817
Synonyms: Pontinf
Gene: Ruvbl1  Location: Chr6:88442391-88474548 bp, + strand  Genetic Position: Chr6, 39.51 cM
Alliance: Ruvbl1tm1.1Hlee page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:219468
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 3 was floxed. Flp-mediated recombination removed the neomycin selection cassette. (J:219468)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ruvbl1 Mutation:  52 strains or lines available
References
Original:  J:219468 Boo K, et al., Pontin is required for pre-TCR signaling at the beta-selection checkpoint in T cell development. Biochem Biophys Res Commun. 2014 Apr 25;447(1):44-50
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory