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Myh4tm2(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Myh4tm2(EGFP/cre/ERT2)Wtsi
Name: myosin, heavy polypeptide 4, skeletal muscle; targeted mutation 2, Wellcome Trust Sanger Institute
MGI ID: MGI:5633807
Synonyms: Myh4tm2(EGFP/cre/ERT2)Hmgu
Gene: Myh4  Location: Chr11:67238029-67260446 bp, + strand  Genetic Position: Chr11, 40.59 cM
Mutation
origin
Mutant Cell Line:  CEPD0086_1_D11
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsAccording to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a neomycin resistance cassette inserted in the intron between exons 4 and 5. A single loxP site is inserted in intron 10. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myh4     Summary of all recombinase alleles driven by Myh4.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Myh4 Mutation:  2 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/22/2020
MGI 6.16
The Jackson Laboratory