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Tnfsf13bm2Btlr
Chemically induced Allele Detail
Summary
Symbol: Tnfsf13bm2Btlr
Name: tumor necrosis factor (ligand) superfamily, member 13b; mutation 2, Bruce Beutler
MGI ID: MGI:5632172
Synonyms: applecrisp
Gene: Tnfsf13b  Location: Chr8:10056229-10086000 bp, + strand  Genetic Position: Chr8, 4.55 cM
Alliance: Tnfsf13bm2Btlr page
Mutation
origin
Strain of Origin:  C57BL/6J
Project Collection: Beutler Mutagenetix
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsThe mutation is a T to C transition at base pair 10,031,534 (v38) on Chromosome 8, or base pair 25,342 in the GenBank genomic region NC_000074, corresponding to nucleotide 911 in the mRNA sequence NM_033622, within exon 6 of 7 total exons. The mutation results in a methionine (M) to threonine (T) substitution at amino acid position 232 (M232T) of the protein. (J:220070)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tnfsf13b Mutation:  28 strains or lines available
References
Original:  J:220070 Wang KW, et al., Mutagenetix entry for applecrisp (Last updated April 7, 2015). MGI Direct Data Submission. 2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory