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Stk31tm2Jw
Targeted Allele Detail
Nomenclature
Symbol: Stk31tm2Jw
Name: serine threonine kinase 31; targeted mutation 2, Jeremy Wang
MGI ID: MGI:5629553
Gene: Stk31  Location: Chr6:49395604-49469501 bp, + strand  Genetic Position: Chr6, 23.87 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:213823
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin resistance cassette replaced exons 17 through 21, which encodes for part of the kinase domain. Western blot analysis confirmed the absence of protein expression in testes. (J:213823)
Generation of the Stk31tm2Jw allele
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk31 Mutation:  39 strains or lines available
References
Original:  J:213823 Zhou J, et al., STK31/TDRD8, a germ cell-specific factor, is dispensable for reproduction in mice. PLoS One. 2014;9(2):e89471
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory