Prepl^tm1.1Sagh
Targeted Allele Detail

Summary

• Symbol: Prepl^tm1.1Sagh
• Name: prolyl endopeptidase-like; targeted mutation 1.1, Alan Saghatelian
• MGI ID: MGI:5629514
• Gene: Prepl Location: Chr17:85370898-85397669 bp, - strand Genetic Position: Chr17, 55.19 cM
• Alliance: Prepl^tm1.1Sagh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:213429
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Exon 11 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 11. (J:213429)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prepl Mutation: 27 strains or lines available

References

• Original: J:213429 Lone AM, et al., Deletion of PREPl causes growth impairment and hypotonia in mice. PLoS One. 2014;9(2):e89160
• All: 1 reference(s)