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Snai3tm1.1Jhws
Targeted Allele Detail
Nomenclature
Symbol: Snai3tm1.1Jhws
Name: snail family zinc finger 3; targeted mutation 1.1, John Weis
MGI ID: MGI:5619843
Synonyms: Snai3Fl
Gene: Snai3  Location: Chr8:122454208-122460733 bp, - strand  Genetic Position: Chr8, 71.07 cM, cytoband E1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:204710
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129/Sv
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA targeting vector was designed to insert a loxP site followed by a FRT-flanked neomycin resistance (neo) cassette upstream of exon 1, and a second loxP site downstream of exon 1. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 1 floxed. (J:204710)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Snai3 Mutation:  11 strains or lines available
References
Original:  J:204710 Pioli PD, et al., Deletion of Snai2 and Snai3 results in impaired physical development compounded by lymphocyte deficiency. PLoS One. 2013;8(7):e69216
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory