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Ednram1Mhda
Chemically induced Allele Detail
Nomenclature
Symbol: Ednram1Mhda
Name: endothelin receptor type A; mutation 1, Martin Hrabe de Angelis
MGI ID: MGI:5618847
Synonyms: abnormal ear #1, AEA001, EdnraY129F, EdnraY129FMhda, Mhdaaea1
Gene: Ednra  Location: Chr8:77663031-77724464 bp, - strand  Genetic Position: Chr8, 36.63 cM, cytoband C2
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsThe molecular lesion is a A-to-T substitution in codon 386 that alters the encoded residue from an alanine to a threonine (NM_010332.2:c.386A>T, NP_034462.1:p.Tyr129Phe). (J:237903)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 20 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ednra Mutation:  22 strains or lines available
References
Original:  J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/18/2018
MGI 6.12
The Jackson Laboratory