Nsun4^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Nsun4^tm1.1Arte
• Name: NOL1/NOP2/Sun domain family, member 4; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:5618260
• Synonyms: Nsun4^loxP
• Gene: Nsun4 Location: Chr4:115890202-115911076 bp, - strand Genetic Position: Chr4, 53.1 cM
• Alliance: Nsun4^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:211012
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked puromycin resistance gene cassette and a second loxP site into intron 2. Subsequent flp-mediated recombination removed the puro cassette. (J:211012)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nsun4 Mutation: 37 strains or lines available

References

• Original: J:211012 Metodiev MD, et al., NSUN4 is a dual function mitochondrial protein required for both methylation of 12S rRNA and coordination of mitoribosomal assembly. PLoS Genet. 2014 Feb;10(2):e1004110
• All: 1 reference(s)