Gt(ROSA)26Sor^{tm1(Ubc-GPR52/AcGFP)Kohi}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Ubc-GPR52/AcGFP)Kohi}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Hidetoshi Komatsu
• MGI ID: MGI:5618144
• Synonyms: Ubc promoter-neo-hGPR52-AcGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Ubc-GPR52/AcGFP)Kohi} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:214470
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Ubc-GPR52/AcGFP)Kohi} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GPR52 (9293)

  Gpr52

  (MGI:3643278)

• Mutation details: The targeted construct introduced into the locus a Ubc promoter, floxed neomycin resistance cassette and the human Gpr52 gene fused to the AcGFP reporter. (J:214470)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1083 strains or lines available

References

• Original: J:214470 Komatsu H, et al., Anatomical transcriptome of G protein-coupled receptors leads to the identification of a novel therapeutic candidate GPR52 for psychiatric disorders. PLoS One. 2014;9(2):e90134
• All: 1 reference(s)