Tg(Prox1-cre/ERT2)1Tmak
Transgene Detail
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Symbol: |
Tg(Prox1-cre/ERT2)1Tmak |
Name: |
transgene insertion 1, Taija Makinen |
MGI ID: |
MGI:5617984 |
Synonyms: |
Prox1-CreERT2, Tg(Prox1-cre/ERT2)#aTmak |
Transgene: |
Tg(Prox1-cre/ERT2)1Tmak Location: unknown
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Alliance: |
Tg(Prox1-cre/ERT2)1Tmak page
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Strain of Origin: |
Not Specified
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Transgene Type: |
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Transgenic (Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Tg(Prox1-cre/ERT2)1Tmak expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Prox1 (MGI:97772) |
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Mutation details: The BAC clone RP23-190F21 is used to generate a transgene in which a cre/ERT2 fusion was inserted at the Prox1 start codon. Two founders were generated and the one (line 1) with complete recombination in all Prox1-expressing tissues was used for further studies.
(J:218590)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Prox1
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Original: |
J:218590 Bazigou E, et al., Genes regulating lymphangiogenesis control venous valve formation and maintenance in mice. J Clin Invest. 2011 Aug;121(8):2984-92 |
All: |
59 reference(s) |
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