Gt(ROSA)26Sor^{tm4.1(CAG-EGFP/TeNT)Imayo}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm4.1(CAG-EGFP/TeNT)Imayo}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4.1, Itaru Imayoshi
• MGI ID: MGI:5617554
• Synonyms: Gt(ROSA)26Sortm1.1(CAG-EGFP/TeNT)Imayo
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm4.1(CAG-EGFP/TeNT)Imayo} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:210615
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: A vector containing a splice acceptor sequence-puromycin resistance gene, a CAG promoter, a floxed primary stop cassette, an FRT-flanked stop cassette, and EGFP-TeNT (tetanus toxin light chain) -SV40pA cassette was inserted into intron 1 via homologous recombination. Flp mediated recombination removed a stop cassette. Cre mediated recombination will result in the expression of the EGFP/TeNT gene. (J:210615)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1060 strains or lines available

References

• Original: J:210615 Sakamoto M, et al., Continuous postnatal neurogenesis contributes to formation of the olfactory bulb neural circuits and flexible olfactory associative learning. J Neurosci. 2014 Apr 23;34(17):5788-99
• All: 4 reference(s)