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Cd96tm1.1Mjs
Targeted Allele Detail
Nomenclature
Symbol: Cd96tm1.1Mjs
Name: CD96 antigen; targeted mutation 1.1, Mark J Smyth
MGI ID: MGI:5617136
Gene: Cd96  Location: Chr16:46035657-46120251 bp, - strand  Genetic Position: Chr16, 30.45 cM, cytoband B5
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209990
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsAll of exons 1 and 2, including the start site, were replaced with a loxP site flanked neomycin resistance gene cassette. Subsequent cre-mediated recombination removed the neo cassette. (J:209990)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Cd96 Mutation:  26 strains or lines available
References
Original:  J:209990 Chan CJ, et al., The receptors CD96 and CD226 oppose each other in the regulation of natural killer cell functions. Nat Immunol. 2014 May;15(5):431-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory