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Ikzf1tm3Kge
Targeted Allele Detail
Nomenclature
Symbol: Ikzf1tm3Kge
Name: IKAROS family zinc finger 1; targeted mutation 3, Katia Georgopoulos
MGI ID: MGI:5617014
Synonyms: IkE5fl
Gene: Ikzf1  Location: Chr11:11685003-11772926 bp, + strand  Genetic Position: Chr11, 7.02 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:209927
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
    Exon 5, which encodes two Ikaros DNA-binding zinc fingers, was floxed via homologous recombination. (J:209927)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ikzf1 Mutation:  5 strains or lines available
References
Original:  J:209927 Joshi I, et al., Loss of Ikaros DNA-binding function confers integrin-dependent survival on pre-B cells and progression to acute lymphoblastic leukemia. Nat Immunol. 2014 Mar;15(3):294-304
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/04/2020
MGI 6.14
The Jackson Laboratory