Ikzf1^tm2.1Mbu
Targeted Allele Detail

Summary

• Symbol: Ikzf1^tm2.1Mbu
• Name: IKAROS family zinc finger 1; targeted mutation 2.1, Meinrad Busslinger
• MGI ID: MGI:5617011
• Synonyms: Ikzf1^ihCd2
• Gene: Ikzf1 Location: Chr11:11634980-11722926 bp, + strand Genetic Position: Chr11, 7.02 cM
• Alliance: Ikzf1^tm2.1Mbu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:209928
• Parent Cell Line: A9 (ES Cell)
• Strain of Origin: (C57BL/6 x 129P2/OlaHsd)F1

Mutation description

• Allele Type: Targeted (No functional change, Reporter)
• Mutation: Insertion
• Mutation details: An IRES-human CD2 reporter construct and a floxed neo cassette were inserted in the 3' untranslated region via homologous recombination. Cre mediated recombination removed the neo cassette. (J:209928)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ikzf1 Mutation: 30 strains or lines available

References

• Original: J:209928 Schwickert TA, et al., Stage-specific control of early B cell development by the transcription factor Ikaros. Nat Immunol. 2014 Mar;15(3):283-93
• All: 2 reference(s)