Tg(Pdx1-flpo)#Dsa
Transgene Detail

Summary

• Symbol: Tg(Pdx1-flpo)#Dsa
• Name: transgene insertion, Dieter Saur
• MGI ID: MGI:5616872
• Transgene: Tg(Pdx1-flpo)#Dsa Location: unknown
• Alliance: Tg(Pdx1-flpo)#Dsa page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Pdx1-flpo)#Dsa expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Pdx1

• A codon optimized flp recombinase cDNA was placed under the control of the Pdx1 promoter. (J:218155)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Pdx1 (species not specified) Summary of all recombinase alleles driven by Pdx1.

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pdx1-flpo)#Dsa

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:218155 Schonhuber N, et al., A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer. Nat Med. 2014 Nov;20(11):1340-7
• All: 17 reference(s)