Fyb1^tm1Pngr
Targeted Allele Detail

Summary

• Symbol: Fyb1^tm1Pngr
• Name: FYN binding protein 1; targeted mutation 1, Josef M Penninger
• MGI ID: MGI:5616449
• Gene: Fyb1 Location: Chr15:6552334-6692794 bp, + strand Genetic Position: Chr15, 3.19 cM, cytoband A1
• Alliance: Fyb1^tm1Pngr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:146727
• Parent Cell Line: E14K (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Most of exon 1 was replaced with a neomycin selection cassette. (J:146727)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fyb1 Mutation: 41 strains or lines available

References

• Original: J:146727 Griffiths EK, et al., Positive regulation of T cell activation and integrin adhesion by the adapter Fyb/Slap. Science. 2001 Sep 21;293(5538):2260-3
• All: 1 reference(s)