About   Help   FAQ
Selenoptm4.1Rfb
Targeted Allele Detail
Nomenclature
Symbol: Selenoptm4.1Rfb
Name: selenoprotein P; targeted mutation 4.1, Raymond F Burk
MGI ID: MGI:5616347
Synonyms: Sepp1U40S
Gene: Selenop  Location: Chr15:3300249-3309992 bp, + strand  Genetic Position: Chr15, 1.84 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:211934
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsA self excising neo selection cassette was inserted before exon 2 and the codon for the first selenocysteine was altered from TGA to TCA, which encodes serine (U40S). (J:211934)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Selenop Mutation:  19 strains or lines available
References
Original:  J:211934 Kurokawa S, et al., Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1. Free Radic Biol Med. 2014 Apr;69:67-76
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/22/2022
MGI 6.21
The Jackson Laboratory