About   Help   FAQ
Targeted Allele Detail
Symbol: Selenoptm4.1Rfb
Name: selenoprotein P; targeted mutation 4.1, Raymond F Burk
MGI ID: MGI:5616347
Synonyms: Sepp1U40S
Gene: Selenop  Location: Chr15:3300249-3309992 bp, + strand  Genetic Position: Chr15, 1.84 cM
Germline Transmission:  Earliest citation of germline transmission: J:211934
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Inserted expressed sequence)
Mutation:    Insertion
Mutation detailsA self excising neo selection cassette was inserted before exon 2 and the codon for the first selenocysteine was altered from TGA to TCA, which encodes serine (U40S). (J:211934)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Selenop Mutation:  19 strains or lines available
Original:  J:211934 Kurokawa S, et al., Sepp1(UF) forms are N-terminal selenoprotein P truncations that have peroxidase activity when coupled with thioredoxin reductase-1. Free Radic Biol Med. 2014 Apr;69:67-76
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.21
The Jackson Laboratory