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Tnfsf11gum
Spontaneous Allele Detail
Nomenclature
Symbol: Tnfsf11gum
Name: tumor necrosis factor (ligand) superfamily, member 11; gummy
MGI ID: MGI:5614816
Gene: Tnfsf11  Location: Chr14:78277446-78308043 bp, - strand  Genetic Position: Chr14, 41.26 cM
Mutation
origin
Strain of Origin:  STOCK Tg(Myh6-cre)1Jmk/J
Mutation
description
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Inversion
 
Mutation detailsA spontaneous 4.7 kb inversion from Chromosome 14 78,279,775 bp to 78,284,475 bp (GRCm38/mm10) has breakpoints in the introns between exons 2 and 3 and 4 and 5, leaving the exons intact but exons 3 and 4 inverted. (J:223062)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 13 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Tnfsf11 Mutation:  25 strains or lines available
References
Original:  J:223062 Palmer K, et al., Discovery and characterization of spontaneous mouse models of craniofacial dysmorphology. Dev Biol. 2016 Jul 15;415(2):216-27
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory