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Tg(ZP2*)4Dean
Transgene Detail
Nomenclature
Symbol: Tg(ZP2*)4Dean
Name: transgene insertion 4, Jurrien Dean
MGI ID: MGI:5613982
Synonyms: mo/huZP2
Transgene: Tg(ZP2*)4Dean  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(ZP2*)4Dean expresses 1 gene
 
Mutation detailsThe full length sequence of the human ZP2 gene in BAC RP11-1023A8 is modified by replacing the corresponding mouse exons encoding amino acids 18-156 (bp 1 in exon 2 to bp 150 in exon 5) for the human amino acids 22-161 (bp 1 in exon 2 to bp 152 in exon 5) at the N-terminus of gene. (J:215794)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:215794 Avella MA, et al., A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. J Cell Biol. 2014 Jun 23;205(6):801-9
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/30/2021
MGI 6.16
The Jackson Laboratory