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Targeted Allele Detail
Symbol: Arntltm1.2Shbi
Name: aryl hydrocarbon receptor nuclear translocator-like; targeted mutation 1.2, Shigeki Shimba
MGI ID: MGI:5613363
Synonyms: Bmal1-
Gene: Arntl  Location: Chr7:113207465-113314126 bp, + strand  Genetic Position: Chr7, 59.17 cM, cytoband F2-F3
Germline Transmission:  Earliest citation of germline transmission: J:177865
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of exon 6. An FRT-flanked neomycin cassette with a 3' loxP site was inserted downstream of exon 8. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 6 through 8. (J:177865)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Arntl Mutation:  125 strains or lines available
Original:  J:177865 Shimba S, et al., Deficient of a clock gene, brain and muscle Arnt-like protein-1 (BMAL1), induces dyslipidemia and ectopic fat formation. PLoS One. 2011;6(9):e25231
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory